USAID established its HIV/AIDS portfolio in 1986 and strives for a world where HIV and AIDS are no longer burdens on health and development. As a key implementer of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), USAID's technical expertise and global in-country support are concentrated on the following the technical priorities and areas of emphasis, all with data-driven science at the core.

HIV/AIDS Product Development Research
Prevention, Care and Treatment
Priority Populations, Integration, and Rights
Strategic Information, Evaluation and Informatics
Supply Chain for Health
Systems and Program Sustainability