PMI is a multiagency initiative, led by the U.S. Agency for International Development (USAID) and co-implemented with the U.S. Department of Health and Human Services’ Centers for Disease Control and Prevention (CDC). PMI has strong support from and collaborates closely with the White House and National Security Council, Department of Defense, National Institutes of Health, Peace Corps, and other U.S. government entities. PMI works hand in hand with national malaria programs and supports partner governments’ national malaria strategies. PMI also engages with the Global Fund to Fight AIDS, Tuberculosis, and Malaria (Global Fund); local research institutions and universities; nongovernmental organizations; faith and community groups; and the private sector to strengthen local leadership and wideranging investment in fighting malaria.