U.S. President's Malaria Initiative

When President George W. Bush launched the U.S. President's Malaria Initiative (PMI) in 2005, malaria was killing almost 700,000 people annually across Africa and choking health systems. More than a decade later, malaria mortality has been more than halved and Health workers and ministries of health have the training and tools to control malaria. PMI, led by USAID, and implemented together with the U.S. Centers for Disease Control and Prevention (CDC) within the U.S. Department of Health and Human Services (HHS), has been a key partner in this effort.

PMI Country Funding, 2005-2017

Map showing PMI country funding 2005-2017

PMI works in 24 high-burden focus countries in sub-Saharan Africa and supports two country programs and one regional program in the Greater Mekong Subregion in Asia. Together with partner countries, PMI is working to optimize the use and scale-up of effective tools[CCM1] for the prevention and control of malaria.


In 2015, PMI launched its 6-year strategy for 2015–2020, which takes into account the progress over the past decade and the new challenges that have arisen. The U.S. Government's goal under the PMI Strategy 2015–2020 [PDF, 8.9MB] is to work with PMI-supported countries and partners to further reduce malaria deaths and substantially decrease malaria morbidity, toward the long-term goal of elimination. Strategy objectives:

  1. Reduce malaria mortality by one-third from 2015 levels in PMI focus countries, achieving a greater than 80 percent reduction from PMI’s original baseline levels.
  2. Reduce malaria morbidity in PMI focus countries by 40 percent from 2015 levels.
  3. Assist at least five PMI focus countries to meet the WHO criteria for national or sub-national pre-elimination.

The PMI strategy is also in line with the goals articulated in the Roll Back Malaria Partnership's second generation global malaria action plan, Action and Investment to Defeat Malaria (AIM) 2016–2030: for a Malaria-Free World [PDF, 18.6MB] and the World Health Organization's (WHO's) updated Global Technical Strategy: 2016–2030[PDF, 1.0MB].


Today, PMI’s 27 programs program benefitted more than 480 million people at risk of malaria across sub-Saharan Africa and in targeted communities at risk for malaria in the Greater Mekong Subregion. These investments by PMI and partners are yielding results. According to the 2017 World Malaria Report, between 2006 and 2016:

  • Malaria mortality rates decreased by 54 percent in sub-Saharan Africa; 18 PMI focus countries achieved 17 percent to 74 percent reductions
  • Malaria case incidence decreased by 30 percent in sub-Saharan Africa; 16 PMI focus countries achieved 8 percent to 74 percent reductions
Map showing reduction in all-cause mortality rates in children under 5 years of age in PMI focus countries

The decline in malaria deaths in children has likely contributed greatly to the observed reductions in all-cause under-five mortality observed in many sub-Saharan African countries. To date, excluding the five new PMI countries announced in 2017, all 19 PMI focus countries in Africa have data from paired nationwide surveys that document declines in all-cause mortality rates among children under five years of age.

To learn more about the U.S. President’s Malaria Initiative, visit pmi.gov.

Last updated: June 02, 2019

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