To address health challenges related to rapid urbanization in Ethiopia, the U.S. Agency for International Development (USAID)-supported Strengthening Ethiopia’s Urban Health Program (SEUHP) promotes urban health leadership and enhances implementation capacity in cities and towns across seven regions of Ethiopia. SEUHP extends the commitment of the previous USAID Urban Health Extension Program by providing the Government of Ethiopia, USAID, civil society partners, and urban communities with cost-effective, high quality, and appropriately targeted support and services to improve the roll-out of the Government of Ethiopia’s Urban Health Extension Program (UHEP) and related urban services. Program activities are closely aligned with the PEPFAR blueprint—Creating an AIDS-free Generation—and other PEPFAR guidance, as well as the Government of Ethiopia's strategic priorities at the federal, regional and city/town levels.