In a major policy speech today at the Center for Global Development, USAID Administrator Samantha Power presented a strategic approach for reclaiming and accelerating public health progress around the world. Immediate global action is needed to reverse the staggering decline in global life expectancy and to support health systems weakened by COVID-19, the global food crisis, ongoing conflicts, and a changing climate. USAID’s global health approach will unite around three foundational efforts: 1) Turn COVID-19 into a manageable respiratory illness everywhere; 2) Build up our defenses against new outbreaks and future pandemic threats; 3) Investing in primary health care workers who will be the backbone of health system recovery.