Through the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), USAID works alongside the U.S. Centers for Disease Control and Prevention, Department of Defense, and Peace Corps to reduce new HIV/AIDS infections and provide treatment to people living with HIV. USAID specifically focuses on ensuring access to prevention, care, and treatment services for key populations; care and support for orphans and vulnerable children; and strengthening health systems by improving supply chain systems, community-led monitoring of health services, and sustainable health financing.

Cameroon is a focus country under the President’s Malaria Initiative (PMI). USAID interventions center around strengthening health facility service delivery, implementation of seasonal malaria chemoprophylaxis campaigns, routine mosquito net distribution, support for training, strengthening pharmaceutical management, supply chain and procurement of Insecticide Treated Nets, Rapid Diagnostic Tests, antimalarials, and treatments. 

Cameroon is also a U.S. Global Health Security Agenda (GHSA) Intensive Support country and has received funding to build its capacity to prevent, detect, and respond to infectious disease threats across animal and human health, including responding to the COVID-19 pandemic.

Finally, USAID implements limited activities to increase access to and use of quality family planning services, improve maternal health, reduce infant mortality, and supports the Cameroonian government to control and eliminate neglected tropical diseases.

Democracy, Peace and Governance 

USAID is working to counter violent extremists’ ability to operate and recruit by supporting local efforts that strengthen service delivery; promoting citizen engagement, participation, and accountability; and building resilience against violent extremism. We partner with traditional leaders, institutions, and networks to promote social and economic inclusion, media and messaging, reconciliation, and conflict mitigation.

Economic Growth and Trade 

USAID’s West Africa Regional Office located in Accra, Ghana, supports opportunities to strengthen leadership and boost business opportunities primarily through the West Africa Trade and Investment Hub and Power Africa.

The Trade Hub helps farmers and firms to compete, attract investment to West Africa, and boost regional and global trade. It offers competitive grants to enable eligible firms from Cameroon to apply for on-demand expertise for exporters on understanding requirements for export to the U.S. market. 

USAID’s Power Africa Off-Grid program accelerates private sector-led energy access in the off-grid market by strengthening institutional and regulatory frameworks, assessing market dynamics, providing intelligence, improving business performance and access to finance, and expanding cross-sectoral integration.


The Central Africa Regional Program for the Environment (CARPE) fosters conservation of the tropical forest in Cameroon and other countries in the Congo Basin. In Cameroon, CARPE works through the United States Forest Service to provide technical assistance to intergovernmental structures to: 1) strengthen the policy and regulatory framework supporting sustainable forest management and biodiversity conservation; 2) build and strengthen capacity at local, national and regional levels to monitor forest cover change, greenhouse emissions and biodiversity. 

Young African Leadership Initiative (YALI)

The YALI program offers interactive and experiential training to participants on business and entrepreneurship, civic leadership, and public management on business and entrepreneurship, civic leadership, and public management through its Regional Leadership Training Centers in Senegal and Ghana. YALI also provides competitive grants to alumni to jumpstart a business, scale up existing businesses or fund small-scale social enterprise activities in their communities.

Humanitarian Assistance

USAID is Cameroon’s leading donor of humanitarian assistance. We provide emergency food and nutrition assistance through market-based interventions that reduce acute food insecurity among the most vulnerable populations. We help build resilient households and communities by supporting disaster risk reduction activities designed to protect and restore livelihood assets. We assist humanitarian partners working in health, nutrition, water, sanitation, and hygiene, as well as in agriculture, food security, protection, humanitarian coordination, and critical air services.